DSPE-PEG-Thiol，DSPE-PEG-SH

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[thiol (polyethylene glycol)]

Synonym: Thiol PEG DSPE, HS PEG DSPE, DSPE PEG SH.

Product Structure:

Product Specifications:

l  Catalog Numbers:PS2-SDE-1K,2K,3K,5K,10K.

l  Appearance: White to off-white or yellowish-white solid.

l  Solubility: 10 mg/mL in hot water, chloroform, DCM.

l  Stability: 1 Years at-20°C, Desiccate.

l  CAS Number: -.

l  Molecular Weight（PEG）:1K,2K,3.4K,5K,10K.

l  Reactive group: Thiol (-SH).

l  Purity: 95%.

Description:

DSPE-PEG-Thiol is one of Ponsure heterobifunctional phospholipid PEG derivatives that have a DSPE lipid and a thiol group linked through a linear PEG chain. DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon saturated phospholipid with high hydrophobicity. PEG chain between DSPE and thiol, on the other hand, offers good hydrophilicity. Thiol functionalized DSPE PEG can be used to react with many thiol reactive groups such as maleimide, pyridyldisulfide or iodoacetamide. It can also be used to bind DSPE PEG to the surface of gold nanoparticles. Reactions between thiol and its reactive partners allow the attachment of DSPE PEG to the targeted material surface. Pegylation significantly suppresses non-specific binding of charged molecules to the surface of modified materials.

Handling and Use:

DSPE-PEG-SH should always be kept in low temperature in dry condition. Prepare fresh solution right before use.Avoid frequent thaw and freezing. For more information about using this product,  visit www.ponsure.com.

Related Products:

DSPE-PEG-NH2, DSPE-PEG-COOH

DSPE-PEG-NHS ,DSPE-PEG-FA

DSPE-PEG-N3,DSPE-PEG-MAL

References：

l  Designer Exosomes for Active Targeted Chemo-Photothermal Synergistic Tumor Therapy------Advanced Functional Materials（IF= 13.325）

This product is for research use only and is not intended for use in humans or for diagnostic use.