Maleimide-PEG-acid，MAL-PEG-COOH

Maleimide (polyethylene glycol) Carboxylic acid

Synonym: Maleimide PEG acid, Mal PEG COOH, Carboxylic acid PEG Maleimide, HOOC PEG Maleimide, Acid PEG Maleimide

Product Structure:

Product Specifications:

l  Catalog Numbers:PS2-MCM-1K,2K,3.4K, 5K,10K.

l  Appearance: White/off-white pale-yellow solid.

l  Solubility: 10 mg/mL in water,chloroform, DMSO.

l  Stability: 1 Years at -20°C, Desiccate.

l  Molecular Weight（PEG）: 1K,2K,3.4K, 5K, 10K.

l  Reactive group: MAL.COOH

l  Reactive to: SH.NH2

Description:

MAL-PEG-COOH is one of Ponsure heterobifunctional polyethylene glycol crosslinkers that contain a thiol reactive maleimide and a carboxylic group. Maleimide group reacts with sulfhydryl groups quickly and specifically at pH 6.5-7.5 while carboxylic group (-COOH) can be activated to react with amine, hydroxy and other functional groups. PEG linker between Maleimide and carboxylic group offers good water solubility, flexible linker structure and enhanced stability.

Handling and Use:

MAL-PEG-COOH  is sensitive to light and temperature. For best use, material should always be kept in low temperature in dry condition.

 Avoid frequent thaw and freezing. For more information about using this product, visit www.ponsure.com.

Storage Conditions：

MAL-PEG-COOH should be stored at -20℃. Desiccate.  Materials may be handled under inert gas for best stability. Re-test material after 12 months.

References：

l  Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine release ------ EBioMedicine (IF=6.183)

l  Angiopep-2 modified PEGylated 2-methoxyestradiol micelles to treat the PC12 cells with oxygen-glucose deprivation/reoxygenation------Colloids and Surfaces B: Biointerfaces (IF=3.997)

Related Products:

BIOTIN-PEG-NH2, DSPE-PEG-NH2

NH2-PEG-SH ,FA-PEG-NH2

FITC-PEG-NH2,LA-PEG-NH2

This product is for research use only and is not intended for use in humans or for diagnostic use.