DSPE-PEG-BIOTIN

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotin(polyethylene glycol)]

Synonym: Biotin PEG DSPE.

Product Structure:

Product Specifications:

l  Catalog Numbers:PS2-BNDE-1K,2K,3K,5K,10K.

l  Appearance: White to off-white solid.

l  Solubility: >5 mg/mL in hot water, chloroform, DCM.

l  Stability: 1 Years at-20°C, Desiccate.

l  CAS Number: 385437-57-0.

l  Molecular Weight（PEG）:1K,2K,3.4K,5K,10K.

l  Functional group: Biotin.

l  Reactive to: Avidin or streptavidin.

l  Purity: 95%.

Description:

DSPE PEG Biotin is one of Nanocs’ functional phospholipid PEG derivatives that have a biotin and a DSPE phospholipid bridged by a linear PEG linker. DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon phospholipid that is highly hydrophobic. PEG backbone, on the other hand, offers good hydrophilicity and water solubility. Biotin is a commonly used bioactive molecule that has high binding affinity toward avidin or streptavidin. Biotin/streptavidin system has been exploited extensively for protein, nucleic acid and many other biomolecule detection and purification. Biotin modified DSPE PEG can be incorporated into liposome and other nanoparticles and thus it can be used to target and detect avidin or streptavidin conjugated substrates.

Handling and Use:

DSPE PEG Biotin should always be kept in low temperature in dry condition. Prepare fresh solution right before use.Avoid frequent thaw and freezing. For more information about using this product,  visit www.ponsure.com.

Related Products:

DSPE-PEG-NH2, DSPE-PEG-COOH

DSPE-PEG-NHS ,DSPE-PEG-FA

DSPE-PEG-SH,DSPE-PEG-MAL

References：

l  Nano-biotinylated liposome-based immunoassay for the ultrasensitive detection of protein biomarker in urine------ Talanta（IF=4.916）.

l  A rapid and efficient technique for liposomal and nonliposomal drug pharmacokinetics studies using magnetic nanoprobes and its application to leakage kinetics of liposomes------ Journal of Chromatography A(IF=3.716).

This product is for research use only and is not intended for use in humans or for diagnostic use.