Folicacid-PEG-amine，FA-PEG-NH2

Amine (polyethylene glycol) folic acid

Synonym: Folate PEGamine, Folate PEG NH2, Amino PEG folate, Folic acid PEG NH2

ProductStructure:

ProductSpecifications:

l CatalogNumbers:PS2-NFA-1K,2K,3.4K,5K,10K.

l Appearance: Orange/yellowto brownish solid.

l Solubility:5mg/mL in hot water, DMSO.

l Stability: 1 Years at-20°C, Desiccate.Protect from light.

l CASNumber:-

l MolecularWeight（PEG）: 1K,2K,3.4K,5K,10K.

l Reactivegroup: Amine (-NH2).

Description:

FA-PEG-NH2  is one of Ponsure reactive folate PEGderivatives that contain a folic acid and a primary amine group on each PEGterminus. Folic acid is also known as vitamin M, vitamin B9 orpteroyl-L-glutamic acid. Folic acid is an essential bioactive molecule for numerousbiological functions. It participates in the synthesis, repairing andmethylation of DNA as well as to act as a cofactor in many biologicalreactions. Amine functionalized folic acid PEG allows the attachment of folicacid to other molecules or materials quickly and efficiently. Flexible PEGchain between amine and folate offers higher water solubility, less sterichindrance and enhanced stability. Molecules or materials conjugated with PEG folicacid is useful for targeted drug delivery, cellular imaging and bioassaydevelopment.

Handlingand Use:

FA-PEG-NH2  is sensitive to light and temperature. Forbest use, material should always be kept in low temperature in dry condition.Protect from light.

 Avoid frequent thaw and freezing. For moreinformation about using this product, visit www.ponsure.com.

StorageConditions：

FA-PEG-NH2 should bestored at -20℃.Desiccate. Protect from light. Materials may be handled under inert gas forbest stability.

References：

l InternationalJournal of New Technology and Research------Preparation of BiodegradableMagnetic  Nanoparticles via a SimpleAssembly Process for  TargetingDoxorubicin Delivery and MR Imaging.

l RSCAdvances------ Surface design andpreparation of multi-functional magnetic nanoparticles for cancer celltargeting, therapy, and imaging.

RelatedProducts:

FA-PEG-NHS, FA-PEG-FITC

FA-PEG-Maleimide ,FA-PEG-Thiol

FA-PEG-COOH,DSPE-PEG-FA

Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.