Methoxy-PEG-Folate，MPEG-FA

Methoxy (polyethylene glycol) folic acid

Synonym: mPEG folate, mPEG folic acid, folic acid PEG

Product Structure:

Product Specifications:

l  Catalog Numbers:PS1-FA-1K,2K,5K,10K,20K,30K

l  Appearance: Yellow to brownish solid.

l  Solubility:5 mg/mL in hot water, DMSO.

l  Stability: 1 Years at-20°C, Desiccate. Protect from light.

l  CAS Number:-

l  Molecular Weight（PEG）: 1K,2K,5K,10K,20K,30K

Description:

MPEG-FA is one of Ponsure methoxypolyethylene glycol folic acid derivatives that have a folic acid molecule covalently attached to a linear PEG linker . Folic acid is also known as vitamin M, vitamin B9 or pteroyl-L-glutamic acid. It is an essential bioactive molecule for numerous biological functions. It participates in the synthesis, repairing and methylation of DNA as well as to act as a cofactor in many biological reactions. Pegylated folic acid is hydrophilic and it is readily soluble in water. Functionalized folic acid PEG derivatives can be used for targeted drug delivery, imaging and bioassay development.

Handling and Use:

For best use, MPEG-FA  should always be kept in low temperature in dry condition. Prepare fresh solution right before use.

Avoid frequent thaw and freezing. For more information about using this product, visit www.ponsure.com.

Storage Conditions：

MPEG-FA should be stored at -20℃. Desiccate. Protect from light. Materials may be handled under inert gas for best stability.

References：

l Acs applied  materials&interfaces------Rational Design of MOF Nanocarrier-Based Co-Delivery System of Doxorubicin Hydrochloride/Verapamil Hydrochloride for Overcoming Multidrug Resistance with Efficient Targeted Cancer Therapy.

l  Materials Science and Engineering C------ Amphiphilic prodrug-decorated graphene oxide as a multi-functional drug delivery system for efficient cancer therapy.

l  Journal of Molecular Liquids----- Active-targeting docetaxel-loaded mixed micelles for enhancing antitumor efficacy.

l  ACS Biomaterials Science & Engineering----- A Derivative of Epigallocatechin-3-gallatea Encapsulated in ZIF-8 with PEG-FA Modification for Target and pHResponsive Drug Release in Anticancer Research.

l  ChemPlusChem----- Multifunctional Mixed Micelles for Efficient Docetaxol Delivery for Cancer Therapy.

Related Products:

FA-PEG-NHS, FA-PEG-NH2

FA-PEG-Maleimide ,FA-PEG-Thiol

FA-PEG-COOH,DSPE-PEG-FA

This product is for research use only and is not intended for use in humans or for diagnostic use.