Methoxy-PEG-Thiol，MPEG-SH

Methoxy (polyethylene glycol) Thiol

Synonym: Methoxy PEG Thiol, mPEG-SH, Amino PEG, Aminopolyethylene glycol methyl ether, Methoxypolyoxyethylene Thiol, O-(2-Aminoethyl)-O’-methylpolyethylene glycol

Product Structure:

Product Specifications:

l  Catalog Numbers:PS1-S-350,500,550,750,1K,2K,4K,5K,10K.20K,30K.

l  Appearance: White/off-white solid, semi-solid or liquid depends on molecular weight.

l  Solubility: 10 mg/mL in water,chloroform, DMSO.

l  Stability: 1 Years at -20°C, Desiccate.

l  Linear Formula：CH3O(CH2CH2O)nCH2CH2SH.

l  Molecular Weight（PEG）: 350,500,550,750,1K,2K,3.4K,5K,10K.20K,30K.

l  Reactive group: SH.

l  Reactive to: MAL.

l  Purity: > 95%.

Description:

mPEG-SH  is one of Ponsure thiol/sulfhydryl (-SH) functionalized polyethylene glycol derivatives that can be used to modify proteins, peptides, particles and other materials with its free thiol group. Thiol group has high affinity toward gold surfaces and this material has been widely used for gold particle and gold film surface modification. In addition, thiol group can react with many other thiol reactive groups, such as maleimide, iodoacetyle, pyridyldithio, etc. Reaction between thiol and above groups allows quick and efficient attachment of PEG chain to the targeted substrates.

Handling and Use:

mPEG-SH  is sensitive to light and temperature. For best use, material should always be kept in low temperature in dry condition.

 Avoid frequent thaw and freezing. For more information about using this product, visit www.ponsure.com.

Storage Conditions：

mPEG-SH should be stored at -20℃. Desiccate.  Materials may be handled under inert gas for best stability. Re-test material after 12 months.

References：

l  Melanin-Like Nanoparticles Decorated with An Autophagy-Inducing Peptide for Efficient Targeted Photothermal Therapy------ Biomaterials (IF=10.273)

l  Immobilized liquid metal nanoparticles with improved stability and 2 photothermal performance for combinational therapy of tumor------ Biomaterials (IF=10.273)

l  Photo-controlled liquid metal nanoparticle-enzyme for starvation/photothermal therapy of tumor by win-win cooperation----- Biomaterials (IF=10.273)

l  Injectable, NIR/pH-Responsive Nanocomposite Hydrogel as Long[1]Acting Implant for Chemo-Photothermal Synergistic Cancer Therapy------Acs applied  materials&interfaces (IF=8.097)

l  A tungsten nitride-based degradable nanoplatform for dual-modal image-guided combinatorial chemo-photothermal therapy of tumors------ Nanoscale (IF=7.233)

l  Molecular imaging of telomerase and the enzyme activity[1]triggered drug release by using a conformation-switchable------ Scientific reports (IF=4.122)

l  Facile synthesis of thiol-polyethylene glycol functionalized magnetic titania nanomaterials for highly efficient enrichment of N-linked glycopeptides------Journal of Chromatography A (IF=3.716)

Related Products:

SH-PEG-COOH, DSPE-PEG-SH

SH-PEG-SH ,FA-PEG-SH

FITC-PEG-SH,LA-PEG-SH

This product is for research use only and is not intended for use in humans or for diagnostic use.