Methoxy-PEG-Maleimide，MPEG-MAL

Methoxy (polyethylene glycol) Maleimide

Synonym: Methoxy PEG Maleimide, mPEG-Mal, MeO-PEG-Mal, PEG maleimide, Maleimide PEG, Maleimide polyethylene glycol methyl ether

Product Structure:

Product Specifications:

l  Catalog Numbers:PS1-M-350,500,550,750,1K,2K,4K,5K,10K.20K,30K.

l  Appearance: White/off-white solid, semi-solid or liquid depends on molecular weight.

l  Solubility: 10 mg/mL in water,chloroform, DMSO.

l  Stability: 1 Years at -20°C, Desiccate.

l  CAS number: 99126-64-4.

l  Linear Formula：CH3O(CH2CH2O)nCH2CH2MAL.

l  Molecular Weight（PEG）: 350,500,550,750,1K,2K,3.4K,5K,10K.20K,30K.

l  Reactive group: MAL.

l  Reactive to: SH.

l  Purity: > 95%.

Description:

mPEG-MAL  is one of Ponsure thiol reactive pegylation reagents that contain a terminal maleimide group. Maleimide reacts with free sulfydryl/thiol group at pH 6.5-7.5 quickly and efficiently. Reaction of maleimide and thiol results a stable, non-cleavable thioether bond. The linear, hydrophilic polyethylene glycol linked to maleimide imparts good water solubility that can be transferred to the pegylated molecules. Maleimide PEG is one of the most frequently used sitespecific pegylation reagents due to its high reactivity and specificity to sulfhydryl from cysteine residues contained in peptides, proteins, antibodies and many other materials. Compared to other pegylation reagents, our Maleimide PEG products have high purity, narrow molecular weight distribution and excellent reactivity. More notably, these maleimide PEGs are soluble in water and all reactions can be carried out in aqueous buffer without need adding any organic solvents.

Handling and Use:

mPEG-MAL  is sensitive to light and temperature. For best use, material MALould always be kept in low temperature in dry condition.

 Avoid frequent thaw and freezing. For more information about using this product, visit www.ponsure.com.

Storage Conditions：

mPEG-MAL MALould be stored at -20℃. Desiccate.  Materials may be handled under inert gas for best stability. Re-test material after 12 months.

References：

l  A facile one-step gelation approach simultaneously combining physical and chemical cross-linking for the preparation of injectable hydrogels------Journal of Materials Chemistry B (IF=4.776)

Related Products:

MAL-PEG-COOH, DSPE-PEG-MAL

MAL-PEG-MAL ,FA-PEG-MAL

FITC-PEG-MAL,LA-PEG-MAL

This product is for research use only and is not intended for use in humans or for diagnostic use.